Study model
Researchers used a partial sciatic nerve ligation rat model and intravenously administered human adipose- or umbilical-cord-derived MSCs.
Assessments included mechanical pain response, ATF-3 expression in dorsal-root ganglia and myelin-related protein in the sciatic nerve.
Meaning and limitations
The source reported reduced pain response and changes in neural-injury markers, supporting further investigation of anti-inflammatory and neuroprotective mechanisms.
Animal data generate hypotheses; translational and clinical studies are required before considering human use.
Editorial note
BIO ISC has editorially summarized this partner source for general information. It is not a substitute for medical advice, diagnosis or treatment.